Our Research At Brooklyn College
Positions are available
We are seeking motivated undergraduate students, Ph.D. candidates and postdocs who are interested in cell cycle research. Please send us your CV and a summary of your research interest.
The cell cycle is an ordered set of processes by which one cell divides into two identical daughter cells. Cell cycle progression is driven by Cyclin/CDK complexes. Ikui's research studies how cells coordinate cell cycle progression to maintain genome integrity in S. cerevisiae and Chlamydomonas.
A control of DNA replication by Cdk1 and GSK-3
A role of PP2A phosphatase during cell cycle
Regulation of DNA replication upon environmental stress
Cell cycle regulation in green algae
Please check our recent work about spindle elongation by PP2A phosphatase. https://jcs.biologists.org/content/133/14/jcs243766
Tryptophan confers resistance to SDS-associated cell membrane stress in Saccharomyces cerevisiae https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199484
International Chlamydomonas Meeting was held in Washington DC. Noriko and Amy presented our work on DNA replication control in green algae.
Stephen, a Ph.D. student from CUNY Biochemistry program, joined our lab. He will study cell size in budding yeast.
We welcomed our new lab member, Noriko Ueki, as a post-doc. She will study DNA replication and cell cycle using Chlamydomonas. Noriko obtained Ph.D. at University of Tokyo in the laboratory of Dr. Ritsu Kamiya.
This image shows how cells send the signal generated from damaged membrane and activate cell cycle checkpoint.
A review paper titled “A new cell cycle checkpoint that senses plasma membrane/cell wall damage in budding yeast” was accepted by BioEssays (update 3/4/2017).
Molecular and Cell Biology Technique course (7150G): We offer 7150G course every fall semester to Master students. We will perform genetic screenings to identify new targets of GSK-3 kinase.
A paper titled ” Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint during G1 in S. cerevisiae“ was accepted by PNAS. (update 5/4/2016)