February 27, 2017

Publication

Schroeder L, Ikui AE. Tryptophan conferes resistane to SDS-associated cell membrane stress in Saccharomyces cerevisiae. PLoS ONE (2019) e0199484. doi: 10.1371/journal.pone.0199484

Kono K, Ikui AE. A new cell cycle checkpoint that senses plasma membrane/cell wall damage in budding yeast. BioEssays (2017) 39(4) doi: 10.1002/bies.201600210 

Kono K, Al-Zain A, Schroeder L, Nakanishi M, Ikui AE. Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint during G1 in S. cerevisiae. PNAS (2016) 113(25) 6910-15. 

Al-Zain A, Schroeder L, Sheglov A, Ikui AE. Cdc6 degradation requires phospho-degron created by GSK-3 and Cdk1 for SCFCdc4 recognition in S. cerevisiae. MBoC. (2015) 26.14: 2609-19. 

Ikui AE, Rossio V, Schroeder L, Yoshida S. A Yeast GSK-3 Kinase Mck1 Promotes Cdc6 Degradation to Inhibit DNA Re-Replication.PLoS Genetics. (2012) 8(12): e1003099. 

Yang CP, Liu L, Ikui AE, Horwitz SB. The interaction between mitoticcheckpoint proteins, CENP-E and BubR1, is diminished in epothiloneB-resistant A549 cells. Cell Cycle. (2010) 9:1207-1213. 

Ikui AE, Cross FR. Specific genetic interactions between spindleintegrity checkpoint proteins and B-type cyclins in Saccharomycescerevisiae. Genetics (2009) 183: 51-61 

Ikui AE, Archambault V, Drapkin BJ, Campbell V, Cross FR. Cyclin andCdk substrate requirements for preventing re-replication reveal theneed for concomitant activation and inhibition.Genetics (2007)175(3):1011-22 

Ikui AE, Yang CPH, Matsumoto T, Horwitz SB. Low Concentrations ofTaxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDCfrom Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leadingto Aneuploidy. Cell Cycle (2005) 4:1385-1388

Archambault V*, Ikui AE*, Drapkin BJ, Cross FR. Disruption ofmechanisms that prevent re-replication triggers a DNA damage response.Mol Cell Biol (2005) 25: 6707-6721 *These authors contributed equallyto this work. 

Christov K, Ikui A, Shilkaitis A, Green A, Yao R, You M, Grubbs C,Steele V, Lubet R, Weinstein IB. Cell proliferation, apoptosis, andexpression of cyclin D1 and cyclin E as potential biomarkers intamoxifen-treated mammary tumors. Breast Cancer Res Treat (2003)77(3):253-264

Ikui AE, Furuya K, Yanagida M and Matsumoto T. Control of localizationof a spindle checkpoint protein, Mad2, in fission yeast.J Cell Sci(2002) 115:1603-10

Ikui AE, Yao Y, Zhou P and Weinstein IB. Induction of apoptosis bysulindac sulfide in HL60 cells is enhanced by p21CiP1 or p27KiP1.Anticancer Res (2001) 21(4A):2297-303.

Slosberg ED, Yao Y, Xing F, Ikui A, Jirousek MR and Weinstein IB. Theprotein kinase C beta-specific inhibitor LY379196 blocks TPA-inducedmonocytic differentiation of HL60 cells the protein kinase Cbeta-specific inhibitor LY379196 blocks TPA-induced monocyticdifferentiation of HL60 cells. Molecular Carcinog(2000) 27(3):166-76

Awards, Honors and Fellowships

Current: NIH SC1 grant. 2017-21

Past:

NIH SC3 grant. 2013-17

PSC-CUNY enhanced award. 2013

PSC-CUNY enhanced award. 2012

NIH SC2 grant. 2010-13

PSC-CUNY Award. 2010

PSC-CUNY Award. 2009

Charles Revson Postdoctoral Fellowship. 2004